A group of humans arrive on Sirius 6-B to investigate an SOS signal sent out from the planet, which has been supposedly deserted since the destruction of the man-made weapons known as “screamers.” Once the squad arrives, they find a group of human survivors eking out an existence in an old military outpost.

The modern-day descendant of Little Red Riding Hood brings her fiancé home to meet her family and reveal their occupation as werewolf hunters, but after he is bitten by a werewolf, she must protect him from her own family.

Following Jigsaw’s grisly demise, Detective Mark Hoffman is commended as a hero, but Agent Strahm is suspicious, and delves into Hoffman’s past. Meanwhile, another group of people are put through a series of gruesome tests.